Epstein File EFTA00591446: Ro Khanna, Susan Wild and Khanna (DS9)

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Epstein File EFTA00591446: Ro Khanna, Susan Wild and Khanna (DS9)

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Technical genetic research excerpt discussing DNA repair mechanisms, specifically non-homologous end joining (NHEJ) and its role in creating small insertion/deletion mutations.

👤 Named in This Document

Susan Wild Wild Ro Khanna

🔑 Evidence Keywords

insertion perform targeted

📋 Key Excerpts9

PersonKeyword

Excerpt 1

Alternatively, repair by non- 256 homologous end joining (NHEJ) produces a small **insertion**/deletion mutation, protecting the site from future 257 recognition

Excerpt 2

**Khanna**, K. K. & Jackson, S. P. DNA double-strand breaks: signaling, repair and the 232 cancer connection. Nat. Genet. 27, 247-254 (2001). 233 22.

Excerpt 3

RD C DD d Genotype AA AD AR DD DR RR AD Fitness 1 1-c 1-s 249 1.p 1 1-c 1-c RD 250 Figure 1 I Endonuclease gene drives undergo biased inheritance in **wild**